Dr. David Alcantara
08/2010-present President of SACSIS
03/2013-03/2015 Senior Marie Curie Research Fellow position at Andalusian Center for Nanomedicine (Bionand): Magnetic PCR project
01/2012-01/2013 Marie Curie Fellow position at Institute of Nanoscience of
Aragon. University of Zaragoza.
01/2010-12/2011 Marie Curie Fellow
position at Center for Nuclear Medicine and Molecular Imaging Research.
Harvard Medical School
05/2009-12/2009 Fulbright Postdoctoral
position at Center for Molecular Imaging Research. Harvard Medical
School
10/2008-4/2009 CNRS Postdoctoral position at
Laboratoire de Résonance Magnétique des Systémes Biologiques (RMSB),
Université Victor Segalen Bordeaux II–CNRS
- D. Alcantara, S Lopez, ML García-Martín, D. Pozo “Iron Oxide Nanoparticles as magnetic relaxation switching (MRSw) sensors: Current applications in Nanomedicine “Nanomedicine: Nanotechnology, Biology and Medicine, 2016, 12, 5, 1252-1262
- D. Alcantara “A new type of journal on Nanotechnology”All Res. J. Nano, 2015, 1, 1, 1-2
- D. Alcantara “Thank you to reviewers of negative results in 2015”All Res. J. Biol, 2015, 6, 3, 30
- D. Alcantara, Manuel Pernia Leal, Irene Bocanegra, ML García-Martín “Molecular imaging of breast cancer: present and future directions” Frontiers in Chemistry, 2014, 2, 112
- U. Mahmood, P. Heidari, P. Habibolahi, H.Cho, D. Alcantara, L. Josephson “Fluorescent nanoparticle imaging allows non-invasive evaluation of immune cell modulation in esophageal dysplasia” Molecular Imaging, 2014, 13 (3) 1-11
- David Alcantara, Elia Grueso, Paula M Castillo, Rafael Prado-Gotor “AuNP’s-DNA non covalent interactions: Improve of some studies and new avenues of research from negative results” The All Results Journals:Chem, 2013, 4, 1, 1-9
- Nuria O Nuñez, Sara Rivera, David Alcantara, Jesus M de la Fuente, Jorge García-Sevillano, Manuel Ocaña “Surface modified Eu:GdVO4 nanocrystals for optical and MRI imaging” Dalton Transactions, 2013, 42 (30), 10725-10734; DOI: 10.1039/C3DT50676B
- Hoonsung Cho, David Alcantara, Rahul A. Sheth, Howard H. Chen, Peng Huang, Sean B. Andersson, David E. Sosnovik, Umar Mahmood, and Lee Josephson. “High Valency DNA Binding Fluorochrome-Magnetic Nanoparticles” ACS Nano, 2013, Mar 26; 7(3):2032-41.
- Rodriguez-Liviano S, Becerro AI, Alcántara D, Grazú V, de la Fuente JM, Ocaña M. “Synthesis and properties of multifunctional tetragonal Eu:GdPO4 nanocubes for optical and magnetic resonance imaging applications” Inorg. Chem, 2013, 52(2):647-54
- David Alcantara, “A closer look” All Res. J. Biol, 2012, 3, i
- David Alcantara, Yanyan Guo, Hushan Yuan, Craig J. Goergen, Howard Chen, Hoonsung Cho, David E. Sosnovik, Josephson, L. “Fluorochrome-Functionalized
Magnetic Nanoparticles for High-Sensitivity Monitoring of the
Polymerase Chain Reaction by Magnetic Resonance”, Angew. Chem. Int. Ed., 2012, 51, 6904-7 - David Alcantara, Javier Reguera. ” Editorial”, All Res. J. Phys, 2011, 1, 1-3
- Chen, S., Alcantara, D., Josephson, L. “A Magnetofluorescent Nanoparticle for
Cell Labeling by Covalently Linking the Drugs Protamine and Feraheme”, J Nanosci Nanotechnol., 2011, 11 (4), 3058-64 - David Alcantara, Rafael Prado Gotor. ” Editorial”, All Res. J. Chem, 2010, 1, 1-3.
- David Alcantara, Joe Blois, Carlos Ceacero, “Editorial”, All Res. J. Biol, 2010, 1, 1-3.
- Larrosa, Mar; Tomé-Carneiro, Joao; Yañez-Gascón, María; Alcántara, David; Selma, Maria; Beltrán, David; García-Conesa, María-Teresa; Urbán, Cristina; Lucas, Ricardo; Tomas-Barberan, Francisco; Morales, Juan; Espín, Juan Carlos. “Preventive Oral Treatment with Resveratrol Pro-drugs Drastically Reduce Colon Inflammation in Rodents”, Journal of Medicinal Chemistry, 2010, 53 (20), 7365-73.
- Medina I, Alcántara D, González MJ, Torres P, Lucas R, Roque J, Plou FJ, Morales JC. “Antioxidant activity of resveratrol in several fish lipid matrices: effect of acylation and glucosylation” J Agric Food Chem. 2010 Sep 8;58(17):9778-86.
- Ricardo Lucas, Francisco Comelles, David Alcántara, Olivia S. Maldonado, Melanie Curcuroze, Jose Luis Parra and Juan Carlos Morales. “Surface-active properties of lipophilic antioxidants tyrosol and hydroxytyrosol fatty acid esters: a potential explanation for the
nonlinear hypothesis of the antioxidant activity in oil-in-water emulsions”, J Agric Food Chem. 2010 Jul 14;58(13):8021-6 - I. Medina, S. Lois, D. Alcántara, R. Lucas, J. C. Morales “Effect of lipophilization of hydroxytyrosol on its antioxidant activity in fish oils and fish oil-in-water emulsions” J Agr Food Chem , 2009, 57 (20), 9773–9779
- Lucas, Ricardo; Alcántara, David; Morales, Juan C. “A concise synthesis of glucuronide metabolites of biologically relevant dietary bioactive phenolics: hydroxytyrosol, resveratrol and urolithin-B” J Carb Res, 2009, 344, 1340-1346
- David Alcantara, Jesus M. de la Fuente. “Agentes de contraste positivos en
imagen por Resonancia Magnética para la diagnosis del cáncer”, revista eSalud, 2009, 5, 17. - D. Alcántara, J. M. de la Fuente, M. Marradi, M. Garcia-Martin, S. Cerdan, and S. Penadés. “Paramagnetic Gold Glyconanoparticles as New Contrast Agents for Brain Tumour Imaging: the Sugars Control Relaxivities and in vivo Selectivity”. Chem Comm, 2009, 26, 3922-4; DOI: 10.1039/b900957d
- Martina Fuss, David Alcantara, Jesús M. de la Fuente, Pedro M. Enríquez-Navas, Jesús Angulo, Soledad Penadés, Mónica Luna* and Fernando Briones. “3D multilayer self-assembling of maltose neoglycoconjugate disulfides on hydrophobic graphite”, J. Phys. Chem. B, 2008, 112 (37), 11595–11600.
- Fuss, Martina; Alcántara, David; De La Fuente, Jesús; Luna, Mónica; Briones, Fernando; Penadés, Soledad. “Supramolecular self-assembled arrangements of maltose glyconanoparticles”, Langmuir, 2008, 24, 5124-5128.
- Soledad Penadés, J. M. de la Fuente, A. G. Barrientos, Caroline Clavel, O. Martínez-ávila and D. Alcántara. “Multifunctional Glyconanoparticles for application in biology and biomedicine” in Nanomaterials for Application in Medicine and Biology, 2008, pp 93-101.
- J.M. de la Fuente, D.Alcantara, S.Penadés “Cell response against magnetic glyconanoparticles: Does the carbohydrate matter?”, IEEE Trans. in Nanobioscience, 2007, 6, 275-281.
- E. Grueso, D. Alcantara, J. Martinez, M. Mancera, S. Penades, F. Sanchez and R. Pradogotor “A kinetic approach for the study of non-covalent interaction between [Ru(NH3)5pz]2+ and gold nanoparticles” J.Chem.Phys.A, 2007, 111, 9769-9774.
- de la Fuente, J.M, Alcántara D, Eaton, P, Crespo, P, Rojas TC, Fernandez A ,Hernando A, Penades S. “Gold and Gold-iron Magnetic Glyconanoparticles: Synthesis, characterization and magnetic properties”; J.Chem.Phys.B, 2006, 110, 13021-13028
- P.Crespo, M.A.Garcia, E.Fernandez, M.Multigner, D.Alcántara, J.M. de la Fuente, S. Penadés, A.Hernando. “Fe impurities weaken the ferromagnetic behaviour in Au Nanoparticles”, Phys.Rev.Lett., 2006, 97, 17, 177203.
- de la Fuente, J.M.; Alcántara D.; Barrientos, A.G.; García, M.L.; Cerdán S.; Penadés, S. “Glyconanoparticles: New Nanomaterials for Glycoscience Studies”; Glycoconj.J.,2005, 22, 262-263
- F.Garcia Sanchez, A.Navas Diaz, A.F.Gonzalez Diaz, M.C.Torrijas, D.Alcántara, S.A.Eremin “Development of homogeneous phase-modulation fluoroimmunoassay for 2,4-dicholorophenoxyacetic acid”; Analitica Chimica Acta, 1999, 395, 133-142
PATENT PRESENTATIONS
- J.C. Morales , F. Comelles, JL. Parra Juez, D. Alcántara, R. Lucas, O. Sanchez, M. Curcuroze. “Fenoles lipofilicos como surfactants antioxidantes” Patent number: PCT/ES2010/070857, 2010.
- J. C. Morales , J.C. Espin de Gea, I Medina Mendez, M. Larrosa, D. Alcántara, M.J. Yanez ,F. A. Tomas-Barberam,M.J. Gonzalez, M.S. Lois, R. Lucas, M.V. Selma, J. Tome. “Preparacion del piceido-butirato y piceido-octanoato y su uso en enfermedades de origen inflamatorio.”
Patent number: PCT/ES2010/070826, 2009. - David Alcantara, Lee Josephson. ” Nanocompositions for monitoring Polymerase Chain Reactions” Patent number: WO/2012/154555; International Application No.: PCT/US2012/036505. 2012
BOOKS / BOOK CHAPTERS
PRIZES
- Foundation Felix Delgado Bocos, 2012, “Best innovative approach in biomedical science” see link
- Junta de Andalucia, 2009, price for best entrepreneurship, The All Results Journals
- Finalist in “Young Entrepreneur” Prize, Alcala de Guadaira City Council (Spain), 2009, Project: The All Results Journals
- Bancaja Prize 2008 Best Young Entrepreneur, Valencia (Spain), Project: The All Results Journals.
- Best poster performance, Conference: Trends in NanoTechnology, September 2005, Oviedo (Spain)
OTHER ACHIEVEMENTS
2008-present: Editor in Chief, The All Results Journals
2010-present: President of the Society for the Improvement of Science
CONFERENCES AND COMMUNICATIONS
- “Glyconanotechnology: A New Methodology to create Nanoparticles with Applications in Biotechnology and Material Science” David Alcántara, Peter Eaton,Africa G.Barrientos, Jesus M.de la Fuente, Soledad Penadés,. VIII Congreso Nacional de Materiales, 2004, Valencia . Poster
- “Magnetic glyconanoparticles:preparations, characterization and potential applications” David Alcántara, Africa G.Barrientos, Jesús M.de la Fuente, Soledad Penadés. 22nd International Carbohydrate Symposium, Julio 2004, Glasgow (U.K). Poster
- “Magnetic glyconanoparticles:preparation, characterization and MRI applications” David Alcántara,Jesús M.de la Fuente,M.L.García, Sebastián Cerdán and Soledad Penadés. NanoSpain, May 2005, Barcelona. Poster
- Magnetic glyconanoparticles:preparation, characterization and Magnetic Resonance Imaging applications” David Alcántara,Jesús M.de la Fuente,M.L.García, Sebastián Cerdán, Soledad Penadés. Trends in NanoTechnology, September 2005, Oviedo. Poster.
- “Glyconanoparticles: New Materials for Glycoscience Studies” David Alcántara, Africa G.Barrientos, Jesús M.de la Fuente, M.L.García, Sebastián Cerdán, Soledad Penadés. Glyco XVIII: International Symposium on Glycoconjugates, Florencia (Italy), 2005. Poster
- “Glyconanoparticles: a New materials for glyconsciences studies” Jesus M. de la Fuente, David Alcántara, Africa G.Barrientos,M.L.García, Sebastián Cerdán, Soledad Penadés. Simposio Severo Ochoa: ” Ochoa 100 años : Mirando al futuro”, Madrid, November 2005. Poster
- “Water Soluble Glyconanoparticles: synthesis, Characterization, Cell Response and Applications as Contrast Agents for MRI”. de la Fuente, J.M.; Alcántara D.; García, M.L.; Crespo, P.; Hernando, A.; Cerdán, S.; Penadés, S. NanoSpain2006, April 2006, Pamplona. Oral
- “Gold and Gold-Iron Water Soluble Glyconanoparticles: Tools for the emerging Nanomedicine” David Alcántara, Jesus M de la Fuente, Patricia Crespo, Antonio Hernando, M.L.García, Sebastián Cerdán, Soledad Penadés. NanobioEurope2006 ,Grenoble (France). Poster.
- “Water Soluble Glyconanoparticles: Synthesis, Characterization, Cell Response and Applications as contrast Agents for MRI.” de la Fuente, J.M.; Alcántara, D.; García, M.L; Crespo, P.; Hernando, A.; Cerdán, S.; Penadés, S., ICN+T06, Basil (Swizerland), July 2006. Poster.
- “Glyconanoparticle-DNA interactions: an AFM and TEM study” Peter Eaton, Jesus M de la Fuente, Africa G. Barrientos, David Alcantara, Raul V. Duran, Cristina T. Rojo and Soledad Penades. ICN+T06, Basil (Swizerland), July 2006. Poster.
- “Water Soluble Magnetic Glyconanoparticles: Synthesis, Characterization, Cell Response and Applications as contrast Agents for MRI.” David Alcántara, Jesus M de la Fuete and Soledad Penadés, S., VIII Jornadas de Carbohidratos, Alcalá de Henares (Madrid), September 2006. Poster.
- Water Soluble Magnetic Glyconanoparticles: Synthesis, Characterization, Cell Response and Applications as contrast Agents for MRI.” Jesús M de la Fuente. David Alcántara, and Soledad Penades; III Nanospain Workshop, Pamplona (Spain), March 2006. Poster.
- “Glyconanotechnology: A method for the preparation of biofuntional nanoparticles with application in nanomedicine” M. Marradi, O. Martinez-Ávila, D. Alcántara, J. M. de la Fuente and S. Penadés. TNT2007, San Sebastián (Spain), September 2007. Oral.
- “Synthesis of novel resveratrol and hydroxytirosol derivatives: evaluation as food antioxidants” David Alcantara, José Manuel Gallardo, Isabel Medina and Juan Carlos Morales. XXII Bienal de Química Orgánica. Tarragona (Spain), June 2008. Oral
- “Identification of Microorganisms with Magnetic Relaxation Switches” David Alcantara and Lee Josephson. MRS 2010 Fall Meeting, Boston (USA). Oral.
- “Nanoparticles for Cell Labeling: Covalent Attachment of the Drug Protamine to FDA Approved Nanoparticles” Suelin Chen, David Alcantara, Ralph Weissleder and Lee Josephson. MRS 2010 Fall Meeting, Boston (USA). Poster.
- “A sensitive MR method for DNA detection with magnetic nanoparticles” D. Alcantara, Y. Guo, H. Yuan, L. Josephson, BioNanoTech Conference & Expo, June 2011, Boston (USA). Poster
- “PCR monitoring by MR: An ultrasensitive method for DNA detection with magnetic nanoparticles”, D. Alcantara, Y. Guo, H. Yua, L. Josephson. Nanax5 Conference, May 2012, Malaga (Spain). Poster.
- “Errores a evitar para obtener una Marie Curie” David Alcantara. VII Congreso Internacional Federación Española de Biotecnólogos, July 2013, Seville (Spain). Oral
- “Magnetic fluorochrome nanoparticles for an ultrasensitive DNA detection in biological systems” David Alcantara, Hoonsung Cho, Yanyan Guo, Lee Josephson, Maria L. Garcia-Martin. XXXIV Reunión Bienal de la Real Sociedad Española de Química, September 2013, Santander (Spain). Oral
- “Ultrasensitive DNA detection in biological systems using Magnetic fluorochrome nanoparticles” David Alcantara, Hoonsung Cho, Yanyan Guo, Lee Josephson, Maria L. Garcia-Martin. Trends in Nanotechnology, September 2013, Seville (Spain). Oral
- “Magnetic Switches as ultrasensitive DNA detection tool for Nanomedicine” David Alcantara, Hoonsung Cho, Lee Josephson, Maria L. Garcia-Martin. Materials Today Virtual Conference 2013, October 2013. Poster